Growth Studies of Three OX 174 Mutants in tsDNA Mutants of Escherichia coli
نویسنده
چکیده
Three mutants of OX174 were examined for their abilities to grow in temperature-sensitive dnaA, dnaC, dnaE, or dnaG mutants of Escherichia coli. The results indicate that the phage mutants have acquired the ability to grow in some tsDNA mutants that normally block the replication of wild-type OX174. Evidence is presented indicating that the phage mutants contain one or more altered structural proteins. Several models are presented to explain how altered phage structural proteins could affect OX174 replication.
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